ECH1

Across TCGA patient cohorts, ECH1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,257 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ECH1-associated genes across cancer lineages are EIF3K, MED29, and CATSPERG. Each is linked with ECH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ECH1-to-partner and partner-to-ECH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECH1 versus EIF3K in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECH1→partner) and Y-score (partner→ECH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF3K →	+0.571	+0.472	.002	<.001	3	4
OV	MED29 →	+0.840	+0.492	.001	.001	3	4
LSCC	CATSPERG →	+0.511	+0.426	<.001	<.001	3	4
LSCC	LINC01534 →	+0.487	+0.391	.002	.009	3	4
LSCC	RPS16 →	+0.925	+0.461	<.001	.001	3	3
OV	TIMM50 →	+0.897	+0.692	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,257 associations by consensus.

ECH1 vs EIF3K — BRCA

Explore this scatter interactively →