ECEL1

Across TCGA cell cohorts, ECEL1 mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ECEL1-associated genes across cancer lineages are CT47A6, USP17L13, and USP17L17. Each is linked with ECEL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ECEL1-to-partner and partner-to-ECEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT47A6 grouped by ECEL1-low versus ECEL1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECEL1→partner) and Y-score (partner→ECEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CT47A6 →	+0.022	+4.807	<.001	.003	3	2
BLOOD_Leukemia	USP17L13 →	+0.003	+3.969	<.001	.009	3	1
BLOOD_Leukemia	USP17L17 →	+0.003	+4.569	<.001	.003	3	1
LARGE_INTESTINE	CCNC →	+0.605	+3.212	.004	.006	3	1
LARGE_INTESTINE	SNX3 →	+0.584	+3.212	.001	.006	3	1
LARGE_INTESTINE	SNX14 →	+0.566	+3.212	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

CT47A6 by ECEL1 expression — OVARY

Explore this box plot interactively →