ECE1

Across TCGA patient cohorts, ECE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,260 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ECE1-associated proteins across cancer lineages are CLSTN1, PLAU, and TIMP1. Each is linked with ECE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ECE1-to-partner and partner-to-ECE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECE1 versus CLSTN1 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ECE1→partner) and Y-score (partner→ECE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CLSTN1 →	+0.600	+1.264	.004	<.001	3	5
LUAD	PLAU →	+0.884	+0.668	<.001	<.001	3	5
GBM	TIMP1 →	+0.841	+0.565	.003	.002	3	4
UCEC	CUEDC1 →	+0.388	+0.732	<.001	<.001	3	4
CCRCC	FBLIM1 →	+0.641	+0.602	<.001	<.001	3	4
HNSC	GPC4 →	+0.685	+0.654	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,260 associations by consensus.

ECE1 vs CLSTN1 — OV

Explore this scatter interactively →