ECE1

Across TCGA cell cohorts, ECE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,247 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ECE1-associated GO terms across cancer lineages are Substance P catabolic process, Biological process involved in symbiotic interaction, and Viral process. Each is linked with ECE1 in more than 17 cancer types. Because this analysis shows association rather than direction, both ECE1-to-partner and partner-to-ECE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substance P catabolic process grouped by ECE1-low versus ECE1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ECE1→partner) and Y-score (partner→ECE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Substance P catabolic process →	+1.063	+1.708	<.001	<.001	3	18
OVARY	Biological process involved in symbiotic interaction →	+0.110	+1.606	<.001	<.001	3	17
STOMACH	Viral process →	+0.089	+1.869	<.001	<.001	3	17
OVARY	Viral life cycle →	+0.098	+1.820	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Symbiont entry into host →	+0.115	+1.604	<.001	.002	3	16
LUNG_NSCLC_LUSC	Symbiont entry into host cell →	+0.115	+1.604	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,247 associations by consensus.

Substance P catabolic process by ECE1 expression — BLOOD_Leukemia

Explore this box plot interactively →