EBP

Across TCGA patient cohorts, EBP RNA expression is significantly associated with the protein abundance of many other proteins, with 13,905 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EBP-associated proteins across cancer lineages are HMGCS1, FDFT1, and FEN1. Each is linked with EBP in more than 5 cancer types. Because this analysis shows association rather than direction, both EBP-to-partner and partner-to-EBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EBP versus HMGCS1 in OV, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EBP→partner) and Y-score (partner→EBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HMGCS1 →	+0.614	+0.696	<.001	.003	3	6
LSCC	FDFT1 →	+0.893	+0.607	<.001	<.001	3	6
LSCC	FEN1 →	+0.470	+0.399	<.001	<.001	3	6
OV	GPKOW →	+0.334	+0.825	<.001	<.001	3	6
BRCA	NSDHL →	+0.569	+0.528	<.001	<.001	3	6
GBM	XPO5 →	+0.574	+0.426	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,905 associations by consensus.

EBP vs HMGCS1 — OV

Explore this scatter interactively →