EBP

Across TCGA patient cohorts, EBP protein abundance is significantly associated with the RNA expression of many other genes, with 5,323 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EBP-associated genes across cancer lineages are RBMS3-AS2, SUV39H1, and PQBP1. Each is linked with EBP in more than 3 cancer types. Because this analysis shows association rather than direction, both EBP-to-partner and partner-to-EBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EBP versus RBMS3-AS2 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBP→partner) and Y-score (partner→EBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBMS3-AS2 →	-0.580	-0.742	.001	<.001	3	4
OV	SUV39H1 →	+0.527	+0.405	.001	.001	3	3
LSCC	PQBP1 →	+0.380	+0.622	<.001	<.001	3	3
CCRCC	PTBP2 →	-0.401	-0.517	<.001	<.001	3	3
BRCA	TIMM17B →	+0.667	+0.455	<.001	.008	3	3
PDAC	ZNF566 →	-0.372	-0.627	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,323 associations by consensus.

EBP vs RBMS3-AS2 — LSCC

Explore this scatter interactively →