EBNA1BP2

Across TCGA pan-cancer cohorts, EBNA1BP2 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated EBNA1BP2 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EBNA1BP2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated EBNA1BP2 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where EBNA1BP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.606	0.893	<.001	57	view →
CCRCC	DFS	Median	All	0.685	0.919	<.001	42	view →
PDAC	DFS	Median	All	0.207	0.449	.002	38	view →
COAD	DFS	Median	All	1.000	0.887	.022	30	view →
LSCC	DFS	Quartile	II,III,IV	0.945	0.458	.001	18	view →
LUAD	OS	Tertile	II,III,IV	0.389	1.000	.006	17	view →
GBM	DFS	Quartile	All	0.289	0.513	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

EBNA1BP2–HNSC (DFS)

Open the HNSC breakdown →