EBNA1BP2

Across TCGA patient cohorts, EBNA1BP2 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EBNA1BP2-associated genes across cancer lineages are ERK2, JNK_pT183_Y185, and MSH2. Each is linked with EBNA1BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBNA1BP2-to-partner and partner-to-EBNA1BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by EBNA1BP2-low versus EBNA1BP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBNA1BP2→partner) and Y-score (partner→EBNA1BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.252	+3.700	.005	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.191	-2.999	.014	.035	3	1
UCEC	MSH2 →	-0.250	-2.973	.020	.035	3	1
UCEC	Notch1 →	+0.145	+3.013	.027	.018	3	1
UCEC	Caspase-7-cleavedD198 →	+0.904	+3.169	.001	.018	3	1
UCEC	RAD51 →	+0.146	+3.000	.025	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ERK2 by EBNA1BP2 expression — UCEC

Explore this box plot interactively →