EBNA1BP2

Across TCGA cell cohorts, EBNA1BP2 mutation is significantly associated with the drug of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EBNA1BP2-associated genes across cancer lineages are GSK429286A, TL-2-105, and CDK9_5038. Each is linked with EBNA1BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBNA1BP2-to-partner and partner-to-EBNA1BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK429286A grouped by EBNA1BP2-low versus EBNA1BP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBNA1BP2→partner) and Y-score (partner→EBNA1BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK429286A →	+0.337	+2.652	.030	.045	3	1
LARGE_INTESTINE	TL-2-105 →	+0.406	+2.652	.040	.045	2	1
LARGE_INTESTINE	CDK9_5038 →	+0.650	+2.906	.017	.033	1	1
LARGE_INTESTINE	Fedratinib →	+0.573	+2.652	.028	.045	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GSK429286A by EBNA1BP2 expression — LARGE_INTESTINE

Explore this box plot interactively →