EBLN3P

Across TCGA pan-cancer cohorts, EBLN3P RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of EBLN3P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where EBLN3P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EBLN3P is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

HNSC, THCA, and BLCA are the cancer types where EBLN3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EBLN3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.771	<.001	10	view →
THCA	All	II,III,IV	−0.664	<.001	9	view →
BLCA	All	All	+0.513	.002	8	view →
COAD	Male	All	+0.677	<.001	7	view →
STAD	All	II,III,IV	+0.610	<.001	7	view →
BRCA	All	II,III,IV	+0.362	<.001	6	view →
CHOL	All	All	+1.249	.001	4	view →
LIHC	Male	All	+0.669	<.001	4	view →
READ	All	III,IV	+0.630	.025	3	view →
LUAD	All	All	+0.326	<.001	3	view →
PRAD	All	All	+0.393	<.001	2	view →
UCEC	All	All	−0.387	.043	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

EBLN3P–HNSC

Open the HNSC breakdown →