EBLN2

Across TCGA patient cohorts, EBLN2 mutation is significantly associated with the RNA expression of many other genes, with 635 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EBLN2-associated genes across cancer lineages are RNA5SP422, MIR4774, and RN7SKP12. Each is linked with EBLN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBLN2-to-partner and partner-to-EBLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by EBLN2-low versus EBLN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBLN2→partner) and Y-score (partner→EBLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP422 →	+0.283	+7.816	<.001	.008	3	2
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
UCEC	RN7SKP12 →	+0.265	+3.092	<.001	.002	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1
UCEC	DBET →	+0.195	+3.454	.005	.004	3	1
BLCA	RNU6-756P →	+0.333	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 635 associations by consensus.

RNA5SP422 by EBLN2 expression — SKCM

Explore this box plot interactively →