Across TCGA pan-cancer cohorts, EBLN1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of EBLN1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where EBLN1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EBLN1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, BRCA, and KICH are the cancer types where EBLN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EBLN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	+0.045	<.001	11	view →
BRCA	All	III,IV	+0.053	.016	3	view →
KICH	All	All	−0.026	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: EBLN1 RNA expression & survival · all EBLN1 data types