EBF4

Across TCGA cell cohorts, EBF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,489 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EBF4-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of nucleotide-excision repair. Each is linked with EBF4 in more than 13 cancer types. Because this analysis shows association rather than direction, both EBF4-to-partner and partner-to-EBF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by EBF4-low versus EBF4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EBF4→partner) and Y-score (partner→EBF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.192	+2.302	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.192	+2.302	<.001	<.001	3	14
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.113	+1.428	<.001	.001	3	13
OESOPHAGUS	Regulation of myoblast fusion →	+0.111	+1.443	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.070	+1.771	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Mitotic cytokinesis →	+0.073	+1.770	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,489 associations by consensus.

Negative regulation of myoblast fusion by EBF4 expression — OESOPHAGUS

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