EBF2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EBF2 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EBF2-associated genes across cancer lineages are Caspase-7-cleavedD198, eIF4E, and Acetyl-a-Tubulin-Lys40. Each is linked with EBF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBF2-to-partner and partner-to-EBF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBF2→partner) and Y-score (partner→EBF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCaspase-7-cleavedD198 →+2.476+2.824<.001.03432
UCECeIF4E →+0.145+2.598.037.00532
SKCMAcetyl-a-Tubulin-Lys40 →+0.571+2.807.002.00232
UCECmTOR_pS2448 →-0.131-1.893.007.01432
UCECAkt_pT308 →+0.444+1.392.032.01932
UCECShc_pY317 →-0.109-1.584.029.03432
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration