Across TCGA cell cohorts, EBF2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EBF2-associated genes across cancer lineages are MYL1, MS4A2, and MRGPRX1. Each is linked with EBF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBF2-to-partner and partner-to-EBF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBF2→partner) and Y-score (partner→EBF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MYL1 →	+0.401	+3.639	.002	<.001	3	2
BONE	MS4A2 →	+0.022	+4.169	<.001	.008	3	1
BONE	MRGPRX1 →	+0.025	+4.169	<.001	.008	3	1
BONE	CST2 →	+0.345	+4.000	.001	.008	3	1
BONE	CCL19 →	+0.162	+4.000	<.001	.008	3	1
BONE	OR2T5 →	+0.010	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

EBF2 survival (RNA) · tumor vs normal (RNA) · all EBF2 data types