EBF1

Across TCGA cell cohorts, EBF1 mutation is significantly associated with the RNA expression of many other genes, with 313 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EBF1-associated genes across cancer lineages are GALNTL5, GH2, and OR1M1. Each is linked with EBF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBF1-to-partner and partner-to-EBF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNTL5 grouped by EBF1-low versus EBF1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBF1→partner) and Y-score (partner→EBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GALNTL5 →	+0.041	+3.544	.001	.009	3	1
LUNG_NSCLC_LUAD	GH2 →	+0.052	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1M1 →	+0.019	+3.977	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP4-4 →	+0.018	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR14C36 →	+0.012	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR13D1 →	+0.026	+3.760	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 313 associations by consensus.

GALNTL5 by EBF1 expression — LUNG_NSCLC_LUAD

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