EBAG9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EBAG9 mutation is significantly associated with the RNA expression of many other genes, with 540 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EBAG9-associated genes across cancer lineages are RNA5SP412, RN7SKP295, and PYDC2. Each is linked with EBAG9 in more than 1 cancer types. Because this analysis shows association rather than direction, both EBAG9-to-partner and partner-to-EBAG9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by EBAG9-low versus EBAG9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EBAG9→partner) and Y-score (partner→EBAG9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNA5SP412 →+0.168+7.930<.001.00832
BLCARN7SKP295 →+0.177+4.314<.001.00931
BLCAPYDC2 →+0.198+3.680<.001.00931
BLCABCAR1P1 →+0.085+4.435<.001.00231
BLCAMIR3171 →+0.655+4.704<.001.00531
BLCAMIR4641 →+0.629+4.027.003.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

RNA5SP412 by EBAG9 expression — LUAD

Box plot of RNA5SP412 in EBAG9-low vs EBAG9-high samples in LUAD.

Explore this box plot interactively →

Exploration