E2F6P1

Across TCGA pan-cancer cohorts, E2F6P1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated E2F6P1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher E2F6P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated E2F6P1 expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

COAD, ACC, and BLCA are the cancer types where E2F6P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.039	0.871	<.001	90	view →
ACC	OS	Tertile	All	0.114	0.892	<.001	72	view →
BLCA	OS	Tertile	III,IV	0.216	0.658	<.001	63	view →
READ	DFS	Tertile	All	0.082	0.799	<.001	54	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	36	view →
LUSC	DFS	Tertile	All	0.834	0.648	.031	9	view →
GBM	OS	Median	All	0.325	0.457	.017	6	view →
LGG	OS	Tertile	All	0.661	0.892	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

E2F6P1–COAD (OS)

Open the COAD breakdown →