E2F5

Across TCGA patient cohorts, E2F5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,116 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible E2F5-associated proteins across cancer lineages are RBM12B, NBN, and NCOA5. Each is linked with E2F5 in more than 9 cancer types. Because this analysis shows association rather than direction, both E2F5-to-partner and partner-to-E2F5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, E2F5 versus RBM12B in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (E2F5→partner) and Y-score (partner→E2F5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBM12B →	+0.272	+0.573	<.001	<.001	3	10
OV	NBN →	+0.417	+0.822	<.001	<.001	3	8
BRCA	NCOA5 →	+0.248	+0.695	<.001	<.001	3	8
OV	PRKDC →	+0.373	+0.537	<.001	.002	3	8
OV	SCRIB →	+0.478	+0.768	<.001	<.001	3	7
LSCC	NCOA2 →	+0.337	+0.616	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,116 associations by consensus.

E2F5 vs RBM12B — LSCC

Explore this scatter interactively →