E2F5

Across TCGA patient cohorts, E2F5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,089 significant associations in total. GBM shows the largest number of these associations.

The most reproducible E2F5-associated genes across cancer lineages are SET, TLR2, and TERF1. Each is linked with E2F5 in more than 2 cancer types. Because this analysis shows association rather than direction, both E2F5-to-partner and partner-to-E2F5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, E2F5 versus SET in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (E2F5→partner) and Y-score (partner→E2F5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SET →	+0.620	+1.040	.007	<.001	3	3
GBM	TLR2 →	-1.614	-0.683	<.001	<.001	3	3
OV	TERF1 →	+0.593	+0.898	.005	.002	3	3
BRCA	C8orf82 →	+0.761	+0.570	<.001	.004	3	3
GBM	LPCAT2 →	-1.374	-0.805	<.001	<.001	3	3
BRCA	POLR1C →	+0.351	+0.518	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,089 associations by consensus.

E2F5 vs SET — OV

Explore this scatter interactively →