Across TCGA pan-cancer cohorts, E2F4P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of E2F4P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where E2F4P1 RNA is repressed in tumor relative to normal tissue. In most cancer types E2F4P1 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC and THCA are the cancer types where E2F4P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in E2F4P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.012	.007	3	view →
THCA	All	All	−0.017	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: E2F4P1 RNA expression & survival · all E2F4P1 data types