Across TCGA patient cohorts, DZIP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,323 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DZIP3-associated proteins across cancer lineages are IFT122, IFT140, and FOSL2_S120. Each is linked with DZIP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both DZIP3-to-partner and partner-to-DZIP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP3→partner) and Y-score (partner→DZIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IFT122 →	+0.355	+0.559	<.001	<.001	3	5
BRCA	IFT140 →	+0.401	+0.576	<.001	<.001	3	5
UCEC	FOSL2_S120 →	-0.742	-0.635	.002	.006	3	5
UCEC	TTC21B →	+0.256	+0.504	.001	.002	3	5
HNSC	PPIF →	-0.380	-0.458	<.001	<.001	3	4
BRCA	QDPR →	+0.497	+0.474	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,323 associations by consensus.

Exploration

DZIP3 survival (RNA) · tumor vs normal (RNA) · all DZIP3 data types