DZIP1L

Across TCGA cell cohorts, DZIP1L mutation is significantly associated with the RNA expression of many other genes, with 1,178 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DZIP1L-associated genes across cancer lineages are TSPAN16, OR12D3, and NEUROG3. Each is linked with DZIP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both DZIP1L-to-partner and partner-to-DZIP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPAN16 grouped by DZIP1L-low versus DZIP1L-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP1L→partner) and Y-score (partner→DZIP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	TSPAN16 →	+0.039	+3.758	.003	.007	3	2
LUNG_NSCLC_LUAD	OR12D3 →	+0.023	+4.813	<.001	<.001	3	2
URINARY_TRACT	NEUROG3 →	+0.006	+5.087	<.001	.004	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
BREAST	RXFP2 →	+0.018	+3.672	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,178 associations by consensus.

TSPAN16 by DZIP1L expression — BREAST

Explore this box plot interactively →