DZIP1

Across TCGA patient cohorts, DZIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 644 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DZIP1-associated genes across cancer lineages are KCNK10, TCL1A, and FZD3. Each is linked with DZIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DZIP1-to-partner and partner-to-DZIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DZIP1 versus KCNK10 in UCEC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP1→partner) and Y-score (partner→DZIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KCNK10 →	+0.053	+0.554	.001	<.001	3	1
UCEC	TCL1A →	+0.901	+0.651	<.001	.006	3	1
UCEC	FZD3 →	-1.078	-0.794	.001	.008	3	1
UCEC	LILRA1 →	+0.473	+0.592	<.001	<.001	3	1
UCEC	SIGLEC6 →	+0.520	+0.574	.004	<.001	3	1
UCEC	PIK3CG →	+0.971	+0.685	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 644 associations by consensus.

DZIP1 vs KCNK10 — UCEC

Explore this scatter interactively →