DZIP1

Across TCGA patient cohorts, DZIP1 mutation is significantly associated with the RNA expression of many other genes, with 5,954 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DZIP1-associated genes across cancer lineages are EIF3JP1, CENPIP1, and RPL34P19. Each is linked with DZIP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DZIP1-to-partner and partner-to-DZIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF3JP1 grouped by DZIP1-low versus DZIP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP1→partner) and Y-score (partner→DZIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	EIF3JP1 →	+0.102	+3.306	<.001	.002	3	4
BRCA	CENPIP1 →	+0.805	+5.259	<.001	.007	3	3
LIHC	RPL34P19 →	+0.133	+5.268	<.001	.006	3	3
UCEC	DYNLL2 →	+0.464	+2.733	<.001	<.001	3	3
SKCM	MIR103A1 →	+0.070	+2.273	.004	.009	3	3
UCEC	GAR1 →	+0.273	+1.555	.007	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,954 associations by consensus.

EIF3JP1 by DZIP1 expression — BLCA

Explore this box plot interactively →