DZIP1

Across TCGA cell cohorts, DZIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,866 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DZIP1-associated GO terms across cancer lineages are Positive regulation of protein localization to cilium, Positive regulation of sodium ion transport, and rRNA transcription. Each is linked with DZIP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both DZIP1-to-partner and partner-to-DZIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to cilium grouped by DZIP1-low versus DZIP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP1→partner) and Y-score (partner→DZIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of protein localization to cilium →	+0.136	+3.475	.003	<.001	3	12
SOFT_TISSUE	Positive regulation of sodium ion transport →	-0.148	-0.982	.001	<.001	3	11
OESOPHAGUS	rRNA transcription →	+0.149	+2.681	<.001	.005	3	10
URINARY_TRACT	IMP metabolic process →	+0.152	+2.146	.001	.001	3	10
OESOPHAGUS	Microtubule nucleation →	+0.162	+3.366	<.001	<.001	3	10
BREAST	Regulation of telomerase RNA localization to Cajal body →	+0.073	+1.753	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

Positive regulation of protein localization to cilium by DZIP1 expression — OESOPHAGUS

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