DZANK1

Across TCGA pan-cancer cohorts, DZANK1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated DZANK1 data layer compared with 22 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DZANK1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DZANK1 expression acts as an unfavorable survival marker.

LUAD and LSCC are the cancer types where DZANK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.782	0.973	.016	19	view →
LSCC	DFS	Median	All	0.515	0.909	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

DZANK1–LUAD (DFS)

Open the LUAD breakdown →