DZANK1

Across TCGA patient cohorts, DZANK1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,887 significant associations in total. COAD shows the largest number of these associations.

The most reproducible DZANK1-associated genes across cancer lineages are C1orf189, RRAD, and NRXN2. Each is linked with DZANK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DZANK1-to-partner and partner-to-DZANK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DZANK1 versus C1orf189 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZANK1→partner) and Y-score (partner→DZANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C1orf189 →	+1.287	+0.471	<.001	<.001	3	3
UCEC	RRAD →	+2.183	+0.489	<.001	.001	3	3
UCEC	NRXN2 →	+0.795	+0.493	<.001	.001	3	2
UCEC	STX2 →	+0.908	+0.514	.004	.001	3	2
UCEC	TTLL9 →	+1.121	+0.487	<.001	<.001	3	2
UCEC	DYDC2 →	+1.650	+0.540	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,887 associations by consensus.

DZANK1 vs C1orf189 — UCEC

Explore this scatter interactively →