DZANK1

Across TCGA patient cohorts, DZANK1 mutation is significantly associated with the RNA expression of many other genes, with 3,776 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DZANK1-associated genes across cancer lineages are RNU6-1203P, IGHV7-40, and FAM238B. Each is linked with DZANK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DZANK1-to-partner and partner-to-DZANK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1203P grouped by DZANK1-low versus DZANK1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZANK1→partner) and Y-score (partner→DZANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1203P →	+0.498	+3.247	<.001	.001	3	3
BLCA	IGHV7-40 →	+0.692	+2.856	<.001	.007	3	3
BLCA	FAM238B →	+0.595	+3.110	<.001	.004	3	2
BLCA	GCNT1P2 →	+0.067	+3.236	.003	.008	3	2
BLCA	RNA5SP473 →	+0.398	+3.746	.005	.002	3	2
COAD	OR9Q2 →	+0.057	+5.136	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,776 associations by consensus.

RNU6-1203P by DZANK1 expression — SKCM

Explore this box plot interactively →