DZANK1

Across TCGA cell cohorts, DZANK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,528 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DZANK1-associated GO terms across cancer lineages are Regulation of organelle assembly, Regulation of syncytium formation by plasma membrane fusion, and Protein localization to cilium. Each is linked with DZANK1 in more than 12 cancer types. Because this analysis shows association rather than direction, both DZANK1-to-partner and partner-to-DZANK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by DZANK1-low versus DZANK1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DZANK1→partner) and Y-score (partner→DZANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of organelle assembly →	+0.049	+0.930	.002	.001	3	13
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.104	+0.675	.007	.001	2	13
LIVER	Protein localization to cilium →	+0.062	+0.948	.004	<.001	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.111	+0.597	.005	.007	2	12
STOMACH	Promoter clearance during DNA-templated transcription →	+0.137	+1.092	.006	.004	3	11
STOMACH	RNA polymerase II promoter clearance →	+0.137	+1.092	.006	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,528 associations by consensus.

Regulation of organelle assembly by DZANK1 expression — LUNG_SCLC

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