DYSF

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DYSF protein abundance is significantly associated with the RNA expression of many other genes, with 19,767 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DYSF-associated genes across cancer lineages are MEFV, IL6, and HLX. Each is linked with DYSF in more than 7 cancer types. Because this analysis shows association rather than direction, both DYSF-to-partner and partner-to-DYSF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYSF versus MEFV in LSCC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYSF→partner) and Y-score (partner→DYSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMEFV →+0.930+0.612<.001<.00138
LUADIL6 →+1.769+0.504<.001<.00138
CCRCCHLX →+0.552+0.428.002.00138
GBMFCGR2A →+0.928+0.532<.001<.00138
CCRCCCLEC1A →+0.808+0.458<.001<.00138
CCRCCBCL6B →+0.847+0.479<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,767 associations by consensus.

DYSF vs MEFV — LSCC

Per-sample scatter of DYSF vs MEFV in LSCC (Pearson r = 0.76).

Explore this scatter interactively →

Exploration