DYSF

Across TCGA patient cohorts, DYSF mutation is significantly associated with the total protein of many other genes, with 100 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYSF-associated genes across cancer lineages are ASNS, PCNA, and Tuberin_pT1462. Each is linked with DYSF in more than 4 cancer types. Because this analysis shows association rather than direction, both DYSF-to-partner and partner-to-DYSF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by DYSF-low versus DYSF-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYSF→partner) and Y-score (partner→DYSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASNS →	+0.438	+2.700	.004	.005	3	5
UCEC	PCNA →	+0.177	+1.263	.001	.002	3	4
LUAD	Tuberin_pT1462 →	-0.129	-2.000	.036	.008	3	4
UCEC	Cyclin-B1 →	+0.585	+1.402	<.001	<.001	3	4
SKCM	c-Kit →	-0.338	-1.353	.028	.009	3	4
UCEC	GSK-3_pS9 →	-0.222	-1.152	.031	.044	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

ASNS by DYSF expression — LUAD

Explore this box plot interactively →