DYRK4

Across TCGA patient cohorts, DYRK4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,592 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DYRK4-associated proteins across cancer lineages are TIGAR, CEP170, and WBP11. Each is linked with DYRK4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DYRK4-to-partner and partner-to-DYRK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYRK4 versus TIGAR in OV, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK4→partner) and Y-score (partner→DYRK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TIGAR →	+0.468	+0.690	<.001	<.001	3	5
COAD	CEP170 →	+0.346	+0.700	<.001	.001	3	5
OV	WBP11 →	+0.268	+0.652	.001	<.001	3	4
CCRCC	CD163 →	+0.728	+0.302	<.001	<.001	3	4
COAD	ERC1 →	+0.276	+0.740	<.001	<.001	3	4
LSCC	USP13 →	+0.359	+0.396	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,592 associations by consensus.

DYRK4 vs TIGAR — OV

Explore this scatter interactively →