DYRK3

Across TCGA cell cohorts, DYRK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,983 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DYRK3-associated GO terms across cancer lineages are Protein localization to cilium, Protein localization to non-motile cilium, and Intraciliary transport involved in cilium assembly. Each is linked with DYRK3 in more than 13 cancer types. Because this analysis shows association rather than direction, both DYRK3-to-partner and partner-to-DYRK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by DYRK3-low versus DYRK3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK3→partner) and Y-score (partner→DYRK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein localization to cilium →	+0.075	+1.699	.001	.003	3	14
STOMACH	Protein localization to non-motile cilium →	+0.077	+1.287	<.001	.002	3	13
LIVER	Intraciliary transport involved in cilium assembly →	+0.106	+1.301	<.001	<.001	3	13
OESOPHAGUS	Protein localization to ciliary membrane →	+0.131	+1.501	.001	.001	3	12
LUNG_NSCLC_LUAD	Intraciliary anterograde transport →	+0.083	+1.380	<.001	<.001	3	11
LARGE_INTESTINE	Intraciliary transport →	+0.058	+0.947	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,983 associations by consensus.

Protein localization to cilium by DYRK3 expression — LIVER

Explore this box plot interactively →