DYRK1B

Across TCGA patient cohorts, DYRK1B RNA expression is significantly associated with the protein abundance of many other proteins, with 12,700 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYRK1B-associated proteins across cancer lineages are SF3B3, SAE1, and ADNP. Each is linked with DYRK1B in more than 6 cancer types. Because this analysis shows association rather than direction, both DYRK1B-to-partner and partner-to-DYRK1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYRK1B versus SF3B3 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK1B→partner) and Y-score (partner→DYRK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.258	+0.546	<.001	<.001	3	7
GBM	SAE1 →	+0.321	+0.487	<.001	<.001	3	6
HNSC	ADNP →	+0.336	+0.949	<.001	<.001	3	6
OV	TBCB →	+0.444	+1.158	.001	<.001	3	5
GBM	TRIM28 →	+0.405	+0.550	<.001	<.001	3	5
GBM	ACIN1 →	+0.251	+0.434	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,700 associations by consensus.

DYRK1B vs SF3B3 — GBM

Explore this scatter interactively →