DYRK1B

Across TCGA patient cohorts, DYRK1B protein abundance is significantly associated with the RNA expression of many other genes, with 11,149 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DYRK1B-associated genes across cancer lineages are EEF1AKMT2, LYPD5, and ZNF391. Each is linked with DYRK1B in more than 2 cancer types. Because this analysis shows association rather than direction, both DYRK1B-to-partner and partner-to-DYRK1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYRK1B versus EEF1AKMT2 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK1B→partner) and Y-score (partner→DYRK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EEF1AKMT2 →	+0.342	+0.217	<.001	<.001	3	3
LUAD	LYPD5 →	-0.699	-0.289	<.001	.003	3	2
PDAC	ZNF391 →	-0.953	-0.618	<.001	.002	3	2
BRCA	INTS6L →	-0.598	-0.493	<.001	<.001	3	2
CCRCC	GLS →	+0.608	+0.498	.001	.007	3	2
LUAD	SFRP5 →	+0.880	+0.296	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,149 associations by consensus.

DYRK1B vs EEF1AKMT2 — GBM

Explore this scatter interactively →