DYRK1B

Across TCGA patient cohorts, DYRK1B mutation is significantly associated with the RNA expression of many other genes, with 2,080 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYRK1B-associated genes across cancer lineages are KRTAP11-1, DBF4P3, and RN7SL422P. Each is linked with DYRK1B in more than 2 cancer types. Because this analysis shows association rather than direction, both DYRK1B-to-partner and partner-to-DYRK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP11-1 grouped by DYRK1B-low versus DYRK1B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK1B→partner) and Y-score (partner→DYRK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	KRTAP11-1 →	+2.463	+4.758	<.001	.003	3	3
OV	DBF4P3 →	+0.060	+5.215	<.001	.007	3	2
OV	RN7SL422P →	+0.138	+7.942	<.001	<.001	3	2
BLCA	SSXP9 →	+0.165	+5.147	<.001	.003	3	2
BLCA	RN7SL454P →	+0.515	+4.238	<.001	.008	3	2
UCEC	CXCL13 →	+1.726	+3.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,080 associations by consensus.

KRTAP11-1 by DYRK1B expression — BLCA

Explore this box plot interactively →