DYRK1B

Across TCGA cell cohorts, DYRK1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,850 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DYRK1B-associated GO terms across cancer lineages are Protein polyubiquitination, Process utilizing autophagic mechanism, and Autophagy. Each is linked with DYRK1B in more than 14 cancer types. Because this analysis shows association rather than direction, both DYRK1B-to-partner and partner-to-DYRK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by DYRK1B-low versus DYRK1B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYRK1B→partner) and Y-score (partner→DYRK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein polyubiquitination →	+0.067	+2.171	.001	<.001	3	15
KIDNEY	Process utilizing autophagic mechanism →	+0.072	+1.472	<.001	<.001	3	13
KIDNEY	Autophagy →	+0.072	+1.472	<.001	<.001	3	13
OVARY	Regulation of myoblast fusion →	+0.121	+1.706	<.001	<.001	3	13
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.072	+1.486	<.001	<.001	3	13
LUNG_SCLC	Golgi to vacuole transport →	+0.109	+1.000	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,850 associations by consensus.

Protein polyubiquitination by DYRK1B expression — STOMACH

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