DYNLT1

Across TCGA pan-cancer cohorts, DYNLT1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DYNLT1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DYNLT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DYNLT1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

COAD, CCRCC, and LUAD are the cancer types where DYNLT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
CCRCC	OS	Median	All	0.726	1.000	.021	6	view →
LUAD	OS	Tertile	All	0.627	1.000	.008	6	view →
GBM	DFS	Tertile	All	0.228	0.513	.004	6	view →
PDAC	OS	Quartile	All	0.386	0.625	.033	4	view →
LSCC	DFS	Tertile	All	1.000	0.848	.031	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DYNLT1–COAD (DFS)

Open the COAD breakdown →