DYNLT1

Across TCGA patient cohorts, DYNLT1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,429 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNLT1-associated genes across cancer lineages are DYNLT3, DYNC1H1, and TMSB10. Each is linked with DYNLT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DYNLT1-to-partner and partner-to-DYNLT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNLT1 versus DYNLT3 in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLT1→partner) and Y-score (partner→DYNLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DYNLT3 →	-0.861	-0.537	<.001	<.001	3	5
HNSC	DYNC1H1 →	+0.654	+0.332	<.001	.001	3	5
UCEC	TMSB10 →	+1.055	+0.272	<.001	<.001	3	5
BRCA	CXCL14 →	-1.861	-0.266	<.001	.004	3	4
BRCA	FAM241A →	-1.086	-0.409	<.001	<.001	3	4
HNSC	RORA-AS1 →	-0.625	-0.201	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,429 associations by consensus.

DYNLT1 vs DYNLT3 — BRCA

Explore this scatter interactively →