DYNLRB1

Across TCGA patient cohorts, DYNLRB1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,870 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNLRB1-associated genes across cancer lineages are CDC42BPB, BAG5, and CLEC4E. Each is linked with DYNLRB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DYNLRB1-to-partner and partner-to-DYNLRB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNLRB1 versus CDC42BPB in HNSC, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLRB1→partner) and Y-score (partner→DYNLRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDC42BPB →	+0.547	+0.362	.003	<.001	3	5
LSCC	BAG5 →	+0.364	+0.121	.007	.008	3	4
OV	CLEC4E →	-1.092	-0.331	<.001	<.001	3	4
HNSC	CEACAM3 →	-0.629	-0.337	<.001	<.001	3	4
GBM	PNMA1 →	+0.442	+0.196	<.001	.004	3	4
LSCC	PACS2 →	+0.501	+0.172	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,870 associations by consensus.

DYNLRB1 vs CDC42BPB — HNSC

Explore this scatter interactively →