DYNLRB1

Across TCGA patient cohorts, DYNLRB1 mutation is significantly associated with the RNA expression of many other genes, with 1,608 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNLRB1-associated genes across cancer lineages are RNU4-33P, RNU6-206P, and RNU6-39P. Each is linked with DYNLRB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DYNLRB1-to-partner and partner-to-DYNLRB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-33P grouped by DYNLRB1-low versus DYNLRB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLRB1→partner) and Y-score (partner→DYNLRB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-33P →	+0.388	+4.738	<.001	.002	3	2
UCEC	RNU6-206P →	+0.274	+3.923	<.001	.009	3	2
UCEC	RNU6-39P →	+0.605	+2.591	<.001	.004	3	2
COAD	MIR548F5 →	+0.412	+7.741	<.001	.009	3	2
SKCM	GLUD1P9 →	+0.034	+7.816	<.001	.008	3	2
UCEC	OR7E53P →	+0.100	+2.759	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,608 associations by consensus.

RNU4-33P by DYNLRB1 expression — UCEC

Explore this box plot interactively →