DYNLL2

Across TCGA cell cohorts, DYNLL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,971 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DYNLL2-associated GO terms across cancer lineages are Regulation of G1/S transition of mitotic cell cycle, Negative regulation of DNA-templated transcription, elongation, and Epigenetic regulation of gene expression. Each is linked with DYNLL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DYNLL2-to-partner and partner-to-DYNLL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G1/S transition of mitotic cell cycle grouped by DYNLL2-low versus DYNLL2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLL2→partner) and Y-score (partner→DYNLL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of G1/S transition of mitotic cell cycle →	+0.063	+0.824	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Negative regulation of DNA-templated transcription, elongation →	+0.125	+0.912	<.001	.004	3	12
LUNG_NSCLC_LUSC	Epigenetic regulation of gene expression →	+0.065	+1.294	.007	<.001	2	13
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.098	+0.830	.001	.002	3	12
LUNG_NSCLC_LUSC	Nuclear envelope organization →	+0.066	+1.144	.003	<.001	3	12
PANCREAS	Negative regulation of cell cycle process →	+0.066	+0.902	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,971 associations by consensus.

Regulation of G1/S transition of mitotic cell cycle by DYNLL2 expression — SOFT_TISSUE

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