DYNLL1

Across TCGA pan-cancer cohorts, DYNLL1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DYNLL1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DYNLL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DYNLL1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where DYNLL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	1.000	0.876	.038	24	view →
LSCC	DFS	Quartile	All	0.945	0.587	.008	22	view →
CCRCC	DFS	Median	All	0.591	0.883	<.001	17	view →
PDAC	OS	Tertile	II,III,IV	0.996	0.668	.009	17	view →
HNSC	DFS	Median	All	0.746	0.527	.003	9	view →
LUAD	DFS	Median	All	0.520	0.831	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DYNLL1–COAD (DFS)

Open the COAD breakdown →