DYNLL1

Across TCGA patient cohorts, DYNLL1 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNLL1-associated genes across cancer lineages are TVP23CP2, RN7SL147P, and RN7SL596P. Each is linked with DYNLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DYNLL1-to-partner and partner-to-DYNLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TVP23CP2 grouped by DYNLL1-low versus DYNLL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLL1→partner) and Y-score (partner→DYNLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TVP23CP2 →	+0.300	+3.815	.004	.001	3	1
UCEC	RN7SL147P →	+0.200	+2.813	.003	.003	3	1
UCEC	RN7SL596P →	+0.227	+2.741	<.001	.004	3	1
UCEC	PGDP1 →	+0.834	+3.266	<.001	.008	3	1
LUAD	SNRPGP16 →	+0.223	+7.930	<.001	.008	3	1
LUAD	OR10AF1P →	+0.069	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

TVP23CP2 by DYNLL1 expression — UCEC

Explore this box plot interactively →