DYNLL1

Across TCGA patient cohorts, DYNLL1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DYNLL1-associated genes across cancer lineages are cDC, pDC, and Th2 cells. Each is linked with DYNLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DYNLL1-to-partner and partner-to-DYNLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cDC grouped by DYNLL1-low versus DYNLL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNLL1→partner) and Y-score (partner→DYNLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cDC →	+0.094	+2.815	.036	.036	3	1
UCEC	pDC →	+0.081	+3.180	.002	.010	3	1
UCEC	Th2 cells →	+0.249	+2.815	.012	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

cDC by DYNLL1 expression — UCEC

Explore this box plot interactively →