DYNC2LI1

Across TCGA pan-cancer cohorts, DYNC2LI1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DYNC2LI1 data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DYNC2LI1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DYNC2LI1 expression acts as an unfavorable survival marker.

KIRC, OV, and SCLC are the cancer types where DYNC2LI1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.266	0.805	.017	12	view →
OV	OS	Median	IV	0.007	0.760	<.001	12	view →
SCLC	OS	Median	All	0.082	0.708	<.001	12	view →
COAD	OS	Median	All	0.578	0.871	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DYNC2LI1–KIRC (OS)

Open the KIRC breakdown →