DYNC2I2

Across TCGA patient cohorts, DYNC2I2 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,826 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DYNC2I2-associated proteins across cancer lineages are DYNC2LI1, DYNC2H1, and DYNC2I1_S247. Each is linked with DYNC2I2 in more than 5 cancer types. Because this analysis shows association rather than direction, both DYNC2I2-to-partner and partner-to-DYNC2I2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC2I2 versus DYNC2LI1 in UCEC, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC2I2→partner) and Y-score (partner→DYNC2I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DYNC2LI1 →	+0.630	+0.384	<.001	<.001	3	6
UCEC	DYNC2H1 →	+0.645	+0.371	<.001	<.001	3	5
UCEC	DYNC2I1_S247 →	+0.772	+0.393	<.001	<.001	3	5
UCEC	DYNC2I1 →	+0.580	+0.444	<.001	<.001	3	4
UCEC	TTC21B →	+0.366	+0.456	<.001	<.001	3	4
UCEC	WDR19 →	+0.405	+0.452	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,826 associations by consensus.

DYNC2I2 vs DYNC2LI1 — UCEC

Explore this scatter interactively →