DYNC2I1

Across TCGA patient cohorts, DYNC2I1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,369 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DYNC2I1-associated proteins across cancer lineages are IFT22, TXNDC5, and MYEF2. Each is linked with DYNC2I1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DYNC2I1-to-partner and partner-to-DYNC2I1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DYNC2I1 versus IFT22 in UCEC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC2I1→partner) and Y-score (partner→DYNC2I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IFT22 →	+0.341	+0.440	.003	.007	3	5
LSCC	TXNDC5 →	-0.499	-0.376	<.001	<.001	3	5
LSCC	MYEF2 →	+0.592	+0.401	<.001	<.001	3	5
PDAC	FKBP11 →	-0.591	-0.411	<.001	<.001	3	5
GBM	SH3BP1 →	-0.368	-0.494	<.001	<.001	3	4
BRCA	HSP90B1 →	-0.328	-0.776	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,369 associations by consensus.

DYNC2I1 vs IFT22 — UCEC

Explore this scatter interactively →