DYNC2I1

Across TCGA cell cohorts, DYNC2I1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,460 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DYNC2I1-associated GO terms across cancer lineages are Intraciliary transport, Cilium movement involved in cell motility, and Pre-mRNA catabolic process. Each is linked with DYNC2I1 in more than 15 cancer types. Because this analysis shows association rather than direction, both DYNC2I1-to-partner and partner-to-DYNC2I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by DYNC2I1-low versus DYNC2I1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DYNC2I1→partner) and Y-score (partner→DYNC2I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Intraciliary transport →	+0.081	+1.202	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.108	-0.962	<.001	<.001	3	16
BONE	Pre-mRNA catabolic process →	+0.202	+0.979	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.102	-0.915	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.102	-0.915	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.105	-0.962	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,460 associations by consensus.

Intraciliary transport by DYNC2I1 expression — BONE

Explore this box plot interactively →